
Timely consultations relevant for family medicine, primary care, and general internal medicine topics for physicians, nurse practitioners, physician assistants, and residents. Offering CME credit for most episodes at https://ce.mayo.edu/podcast. Produced by @MayoMedEd.
Timely consultations relevant for family medicine, primary care, and general internal medicine topics for physicians, nurse practitioners, physician assistants, and residents. Offering CME credit for most episodes at https://ce.mayo.edu/podcast. Produced by @MayoMedEd.
Episodes

21 hours ago
21 hours ago
Host: Darryl S. Chutka, M.D.
Guest: George Wang, M.D.
Bicuspid aortic valve is a relatively common congenital heart disease. It can be associated with other genetic disorders such as Turner’s Syndrome or exist as an isolated entity. In most cases, patients with a bicuspid aortic valve are initially asymptomatic; however later in the course, they may develop symptoms related to a subsequent aortic stenosis or regurgitation. It’s also associated with a dilated ascending aorta with potential rupture if unrecognized. Therefore, it’s in the patient’s best interest to diagnose the condition as early as possible. What are the early symptoms and when should we suspect the patient may have a bicuspid aortic valve? What type of surveillance should be performed and when is surgery indicated? These are some of the questions I’ll be asking my guest, Dr. George Wang, a cardiologist in the Department of Cardiovascular Medicine at the Arizona Campus of the Mayo Clinic as we discuss “Bicuspid Aortic Valve Disease”.
Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development
Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development

3 days ago
3 days ago
Host: Darryl S. Chutka, M.D.
Guest: Julie Rosenthal, M.D.
Cardiac amyloidosis is not a common condition, but it is important for primary care clinicians to recognize it in our patients. It’s commonly underdiagnosed as the symptoms are often assumed to be due to other, more common cardiac problems. Early recognition is important since this can result in improved treatment options and better patient outcomes. So how do we recognize cardiac amyloidosis? What are the presenting symptoms and what’s the best way to establish an accurate diagnosis? I’ll be asking my guest these questions as we discuss cardiac amyloidosis. My guest for tis podcast is Dr. Julie Rosenthal, a cardiologist in the Department of Cardiovascular Medicine at the Arizona campus of the Mayo Clinic.
Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development
Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development

Tuesday Jan 27, 2026
Concussions: What Every Primary Care Provider Should Know
Tuesday Jan 27, 2026
Tuesday Jan 27, 2026
Host: Darryl S. Chutka, M.D.
Guest: Matthew B. Anastasi, M.D.
Patients with concussions are commonly seen in primary care practices and concussions don’t spare any particular age group. Children, young adult athletes and older individuals are all at increased risk. They’re a form of traumatic brain injury and while most are self-limiting, they require an accurate assessment, proper management and appropriate follow-up to make sure the patient is recovering and not experiencing complications. When should we suspect a concussion? What questions should we be asking in order to make an accurate diagnosis? What’s the best management of a patient who has had a concussion and finally, when can that patient return to their normal activities? The topic for this podcast is “Concussions: What Every Primary Care Provider Should Know” and my guest is Dr. Matthew Anastasi, a family medicine and sports medicine physician at the Arizona campus of the Mayo Clinic.
Learn more at https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Jan 20, 2026
Tuesday Jan 20, 2026
Host: Darryl S. Chutka, M.D.
Guest: Stephen Kopecky, M.D.
One of the biggest surprises we’ve seen in medicine in the past several years has been the numerous health benefits realized from the GLP-1 agonists. Originally developed for the management of diabetes, they’ve shown significant potential to improve cardiovascular risks, beyond controlling blood glucose and lowering hemoglobin A1c. Several studies have shown reductions in cardiovascular events including MI, stroke as well as reducing overall cardiovascular death. What is the mechanism of action for these cardiovascular benefits? Are there any differences in the various GLP-1 medications available and who’s a candidate for a GLP-1 medication? I’ll get answers to all of these questions and more in this podcast as I speak with Dr. Stephen Kopecky, a preventive cardiologist at the Mayo Clinic. We’ll be discussing “GLP-1 Agonists and Reducing Cardiovascular Risk”.
Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development
Learn more at https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Thursday Jan 15, 2026
Thursday Jan 15, 2026
Host: Darryl S. Chutka, M.D.
Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B.
The class of medications known as the GLP-1 agonists is very popular with our patients. Although initially indicated for management of diabetes, they’re frequently taken for the weight loss they commonly produce. How long should these medications be taken? Is there anything we can do to help maintain the weight loss achieved with these medications? How significant is the loss of muscle mass which can occur as part of the weight lost with these medications and can this be minimized. Finally, how safe are the compounded and unapproved versions of these medications patients often find more affordable? These are a few of the questions we’ll address in podcast on the GLP-1 medications used for weight loss and we’ll tackle the “Controversies and Future of the GLP-1 Medications”. My guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology at the Mayo Clinic.
Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Jan 13, 2026
Tuesday Jan 13, 2026
Host: Darryl S. Chutka, M.D.
Guest: Tamim Rajjo, M.D., M.P.H.
Using GLP-1 medication for weight loss has become very popular with our patients. In the recent past, this has produced a shortage of these medications available, and those taking them for management of diabetes have found them difficult to obtain. Although in most cases, they are quite successful in producing substantial weight loss, many have regained weight after the medication was discontinued. How much weight can patients expect to lose with these medications? When should these medications be stopped, or should they? Are there strategies that have shown benefit to help patients maintain the weight they lose once the medication is discontinued? This podcast is the second of three on using the GLP-1 medications for weight loss and we’ll discuss “The Importance of Lifestyle Changes with the Use of GLP-1 Medications for Weight Loss”. My guest is Dr. Tamim Rajjo, a physician trained in Preventive Medicine and Obesity Medicine from the Mayo Clinic.
Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Thursday Jan 08, 2026
Thursday Jan 08, 2026
Host: Darryl S. Chutka, M.D.
Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B.
Using GLP-1 medications for weight loss has become extremely popular. Is this the latest fad in losing weight, or will these medications completely change our approach to managing obesity? They do appear to be very effective in promoting substantial weight loss. What is the history of these medications? Are there differences in the various GLP-1 medications available? What are the potential adverse effects of this drug class? This podcast is the first in a series of three on the GLP-1 medications prescribed for weight loss. The topic for this podcast is “Who Is a candidate for a GLP-1 Medication?” and my guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology and Metabolism at the Mayo Clinic.
Check out the series!
Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Jan 06, 2026
The Risks and Benefits of Alcohol
Tuesday Jan 06, 2026
Tuesday Jan 06, 2026
WELCOME TO SEASON 6 OF THE MAYO CLINIC TALKS PODCAST!
Host: Darryl S. Chutka, M.D.
Guest: Warren G. Thompson, M.D.
Alcohol can offer a variety of social and potential health benefits when consumed in moderation. However, alcohol is also associated with a variety of health risks, including addiction, increased likelihood of accidents, impaired judgment, cardiovascular problems, hepatic disease and even malignancy. Other than the social benefits, are there true health benefits of alcohol? Is there an amount of alcohol that’s considered safe? How can we as primary care clinicians convey the health risks of alcohol to our patients? The topic for this podcast is the “Risks and Benefits of Alcohol” and these are some of the questions I’ll be asking my guest, Warren G. Thompson, M.D., an internist and preventive medicine specialist at the Mayo Clinic.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Dec 30, 2025
Re-Release!! "No Loafing Matter" Celiac Disease & Gluten Sensitivity
Tuesday Dec 30, 2025
Tuesday Dec 30, 2025
HAPPY HOLIDAYS! Enjoy this re-release from Season 3 of Mayo Clinic Talks:
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Dec 23, 2025
Re-Release!! "Lettuce Eat" Plant-Based Diets: Healthy and NonHealthy
Tuesday Dec 23, 2025
Tuesday Dec 23, 2025
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Dec 16, 2025
Communication and Hospice
Tuesday Dec 16, 2025
Tuesday Dec 16, 2025
Host: Darryl S. Chutka, M.D.
Guest: Cory Ingram, M.D.
As primary care providers, we have the privilege of guiding our patients through their healthcare journey, healing their medical conditions, managing them through chronic illness and at times, assisting them through the final chapters of their life. The topic for today’s podcast is “Hospice”, an important though often underutilized part of that journey. Hospice is not about giving up, it’s about changing the direction and goal of our care from cure to comfort. It prioritizes quality of life and maintaining dignity for patients going through a very challenging period of their life. My guest is Cory Ingram, M.D., a family medicine and palliative care physician from the Mayo Clinic who has extensive experience and insight into this topic. He’ll guide us through when we should consider hospice, who qualifies for hospice and the importance of good communication skills in helping patients and their families during this last period of their life.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Dec 09, 2025
Nutritional Supplements
Tuesday Dec 09, 2025
Tuesday Dec 09, 2025
Host: Darryl S. Chutka, M.D.
Guest: Andrew R. Jagim, Ph.D.
Nutritional supplements are very popular with our patients. They are supposed to provide benefits that may not be present in our typical diet. Vitamins and minerals are the most common supplements taken, followed closely by sports nutrition products such as protein powders and energy drinks. Consumers buy supplements because they’re readily available, relatively low cost and they believe that supplements will help them achieve health benefits. Patients often assume that supplements are safe, yet some can cause significant health problems, especially when taken in higher doses. Some have the potential to interact with various prescription medications. Are there nutritional supplements our patients should be taking? Which ones are potentially harmful? How safe are these products and do supplements have any regulatory oversight? These are questions I’ll be asking my guest, Andrew R. Jagim, Ph.D., Director of Sports Medicine Research at the Mayo Clinic as we discuss “Nutritional Supplements”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Dec 02, 2025
Provider-Patient Relationship Skills
Tuesday Dec 02, 2025
Tuesday Dec 02, 2025
Host: Darryl S. Chutka, M.D.
Guest: Cory Ingram, M.D.
There are a couple outcomes in taking a medical history. Obviously, one is information gathering. You need to hear the patient’s symptoms to help form your differential diagnosis. The second, and equally important, is to help establish a relationship with that patient. There are several reasons a good provider-patient relationship is important. The patient is more likely to feel positive about their medical encounter, they’re more likely to be adherent to your recommendations regarding their health conditions, and they tend to be more forgiving if they experience an adverse event. What makes up a good provider-patient relationship? What can we do as clinicians to help establish a good relationship with our patients? Can we still establish a good relationship when we practice telemedicine? These are questions I’ll be asking my guest, Cory Ingram, M.D., a palliative care physician at the Mayo Clinic as we discuss “Provider-Patient Relationship Skills”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Nov 25, 2025
Vascular Medicine Series: Lymphedema Challenges and Successes
Tuesday Nov 25, 2025
Tuesday Nov 25, 2025
Host: Darryl S. Chutka, M.D.
Guests: William J. Casey III, M.D. and Andrea L. Cheville, M.D.
There are numerous reasons a patient may develop swelling of an extremity. One of the less common reasons, but often misdiagnosed or undiagnosed is lymphedema. What is lymphedema, why does it occur and who’s at risk for it? Early recognition is important to prevent complications and primary care providers play a crucial role in identifying patients with lymphedema, coordinating their care and providing follow-up. How can we differentiate lymphedema from other causes of swelling? What are the potential complications if lymphedema is not correctly diagnosed and finally, what are some of the latest treatments available for the management of lymphedema? The topic for this podcast is “Lymphedema: Challenges and Success” and my guests include Andrea L. Cheville, M.D., a physician in the Department of Physical Medicine and Rehabilitation and William J. Casey, III, M.D., a physician in the Department of Plastic Surgery, both at the Mayo Clinic.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
To hear more about this series: https://ce.mayo.edu/content/mayo-clinic-talks-vascular-medicine-series

Tuesday Nov 18, 2025
Common Foot Disorders "Agony of De-Feet"
Tuesday Nov 18, 2025
Tuesday Nov 18, 2025
Host: Darryl S. Chutka, M.D.
Guest: Martin G. Ellman, D.P.M.
We don’t really appreciate our feet until they hurt and then we become extremely aware of every step we take. Plantar fasciitis, bunions, metatarsalgia; all foot disorders which can result in foot pain and represent common reasons for an outpatient visit. What’s the role of the primary care clinician in the evaluation of foot pain? How should these conditions be managed? I’ll be reviewing common causes of foot problems as well as the management of foot pain with Martin G. Ellman, D.P.M., a podiatrist at the Mayo Clinic as we discuss “The Agony of De-Feet”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Nov 11, 2025
Alzheimer’s Disease and Family Dynamics
Tuesday Nov 11, 2025
Tuesday Nov 11, 2025
Host: Darryl S. Chutka, M.D.
Guest: Christina Chen, M.D.
Alzheimer’s Disease affects not only the patient but also has a significant impact on that patient’s family. The family becomes stressed as emotional and physical burdens develop. The role of the primary care clinician in managing a patient with Alzheimer’s is not only to care for the patient but also help and support families as they go through a very complex, emotional journey. Today’s podcast will cover the changes in family dynamics which commonly occur in Alzheimer’s Disease including caregiver burden, legal decisions which need to be made, and difficult ethical choices which will be made as the disease progresses. What are some common sources of conflict within families as they care for their loved one with Alzheimer’s? What can we do as a clinician to help families through this difficult journey? How do we approach a situation where there’s disagreement in the family regarding management? These are some of the questions I’ll be asking my guest, Christina Chen, M.D., an internist and geriatrician in the Division of Community Internal Medicine at the Mayo Clinic as we discuss “Alzheimer’s Disease and Family Dynamics”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Nov 04, 2025
Mild Cognitive Impairment
Tuesday Nov 04, 2025
Tuesday Nov 04, 2025
Host: Darryl S. Chutka, M.D.
Guest: Ronald C. Petersen, M.D., Ph.D.
We all experience cognitive changes as we age. If you doubt this, try learning to play the piano with a group of 7-and 8-year-olds and see who sounds best at the recital. We tend to have difficulty with new learning and can struggle with short term memory. When do these cognitive changes become pathologic? Dementia results in a gradual decline in cognitive abilities, memory and behavior, severe enough to interfere with daily life. Between the cognitive changes that occur with aging and those with dementia, there is another medical entity, mild cognitive impairment. How does it differ from the normal cognitive changes of aging? How does it differ from dementia? And is it important for us to recognize it? These are some of the questions I’ll be asking my guest for today’s podcast, Ronald C. Petersen, M.D., Ph.D., a neurologist and internationally recognized expert in the field of dementia as we discuss “Mild Cognitive Impairment”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Thursday Oct 30, 2025
Prostate Cancer
Thursday Oct 30, 2025
Thursday Oct 30, 2025
Host: Darryl S. Chutka, M.D.
Guest: Daniel M. Frendl, M.D., Ph.D.
Prostate cancer is quite common in middle age and older men and represents the second most common malignancy diagnosed in this population. Only skin cancer is more common. Early diagnosis is important and carries an excellent prognosis. There are several management options available for localized disease and some new treatments which can be used for both aggressive and more advanced disease. When should active surveillance be used when prostate cancer has been diagnosed? How does radiation therapy compare to surgical prostatectomy regarding long-term outcomes and what are some of the newer treatment options available for advanced disease? These are some of the questions I’ll be asking my guest, Daniel M. Frendl, M.D., Ph.D., a urologist from the Department of Urology at the Arizona campus of the Mayo Clinic as we discuss “Prostate Cancer”.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Tuesday Oct 28, 2025
Prostate Cancer Screening
Tuesday Oct 28, 2025
Tuesday Oct 28, 2025
Host: Darryl S. Chutka, M.D.
Guest: Daniel M. Frendl, M.D., Ph.D.
If your practice includes middle age and older men, you’ve very likely diagnosed prostate cancer. It’s the most diagnosed non-skin cancer in men in the U.S. Its incidence rises with age, with a median age of around 66 years. When found early, prostate cancer is very treatable, and in most cases, curable. Prostate specific antigen, or PSA is very effective in detecting early prostate cancer, but its use has been controversial due to the risk of overdiagnosis and overtreatment. What are the current recommendations for prostate cancer screening with PSA? What’s the role of the digital rectal exam? How should we be using the PSA and what other tests are available for prostate cancer screening? The topic for this podcast is “Prostate Cancer Screening” and I’ll be asking these questions to my guest, Daniel M. Frendl, M.D., Ph.D., a urologist at the Arizona campus of the Mayo Clinic.
Tune in this Thursday for our next episode on "Prostate Cancer" releasing October 30, 2025.
Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts

Thursday Oct 23, 2025
Obstetric and Gynecologic Health Series: Labor and Delivery
Thursday Oct 23, 2025
Thursday Oct 23, 2025
Guest: Rebecca Smith, Ph. D, APRN, CNM
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
Rebecca Smith provides a comprehensive overview of labor and delivery, including the stages of labor, assessment techniques, and monitoring practices. The episode also addresses potential complications and their management.
Learning Objectives:
- Describe the stages, duration, and monitoring of labor and delivery.
- Compare and contrast complications that may arise during pregnancy and delivery.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Tuesday Oct 21, 2025
Obstetric and Gynecologic Health Series: Complicated Pregnancy
Tuesday Oct 21, 2025
Tuesday Oct 21, 2025
Guest: Julie Lamppa, APRN, CNM
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
Julie Lamppa discusses complications that can arise during pregnancy, including gestational diabetes, preeclampsia, and other abnormalities. This episode emphasizes early recognition and multidisciplinary management.
Learning Objectives:
- Differentiate various pregnancy complications and their clinical implications.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Thursday Oct 16, 2025
Obstetric and Gynecologic Health Series: Gynecologic Pain Disorders
Thursday Oct 16, 2025
Thursday Oct 16, 2025
Guest: Jenna Wygant, APRN, CNP, DNP
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
Jenna Wygant discusses common gynecologic pain disorders such as endometriosis and pelvic inflammatory disease. The episode highlights diagnostic challenges and treatment strategies to improve patient outcomes.
Learning Objectives:
- Identify conditions contributing to gynecologic pain.
- Review signs/symptoms, risk factors, diagnostic approaches, and treatment options.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Tuesday Oct 14, 2025
Obstetric and Gynecologic Health Series: Gynecologic Cancer
Tuesday Oct 14, 2025
Tuesday Oct 14, 2025
Guest: Casey Lawler, P.A.-C
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
This episode provides an overview of gynecologic cancers, including cervical, ovarian, uterine, and vulvar cancers. Casey Lawler shares insights into the causes, risk factors, and clinical management of these conditions.
Learning Objectives:
- Describe the major types of gynecologic cancers.
- Compare and contrast causes, risk factors, signs/symptoms, diagnostic methods, and treatment options.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Tuesday Oct 07, 2025
Obstetric and Gynecologic Health Series: Breast Cancer
Tuesday Oct 07, 2025
Tuesday Oct 07, 2025
Guest: Susan Kok, M.D.
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
Dr. Susan Kok joins the podcast to explore both non-invasive and invasive breast cancers. This episode covers risk factors, symptom recognition, diagnostic tools, and treatment modalities, with a focus on individualized care and shared decision-making.
Learning Objectives:
- Understand the spectrum of non-invasive breast cancers.
- Identify risk factors, symptoms, and diagnostic tools for invasive breast cancers.
- Discuss treatment options tailored to diagnosis and patient preferences.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development

Tuesday Sep 30, 2025
Obstetric and Gynecologic Health Series: Benign Breast Tumor Conditions
Tuesday Sep 30, 2025
Tuesday Sep 30, 2025
Guest: Danielle O’Laughlin, PA-C, MS
Hosts: Danielle O’Laughlin, PA-C, MS and Jenna Wygant, APRN, CNP, DNP
In this episode, Danielle O’Laughlin discusses benign breast tumor conditions and other non-cancerous growths. Listeners will gain insight into the clinical presentation, diagnostic evaluation, and management strategies for these common breast findings.
Learning Objectives:
- Review the types of benign breast tumors and their clinical features.
- Differentiate between symptoms, diagnostic approaches, and treatment options for various benign breast conditions.
Learn more about this series: Mayo Clinic Talks: Obstetric and Gynecologic Health | Mayo Clinic School of Continuous Professional Development
Connect and listen with Mayo Clinic Podcasts | Mayo Clinic School of Continuous Professional Development
