Mayo Clinic Talks

COVID-19 Miniseries Episode 49: Mayo Clinic Q & A - COVID-19 Back-To-School Recommendations

This episode is shared from Mayo Clinic Q&A and was recorded in August, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)

Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)

Whether in person, online or a hybrid model of education, families and school districts are planning for how to safely teach students during the COVID-19 pandemic. No matter which plan is chosen by communities, this school year will be challenging.

On the Mayo Clinic Q&A podcast, Dr. Nipunie Rajapakse, a pediatric infectious disease specialist at Mayo Clinic, discusses how students, teachers and staff can use public health measures already in place to minimize the risk of exposure to the virus and reduce community spread of COVID-19.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Regenerative Medicine Takes on Hair Loss

Guest: Alison J. Bruce, M.B., Ch.B. & Shane A. Shapiro, M.D. 

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Androgenic alopecia can have a significant impact on women across a spectrum of age. The psychological and social impact of hair thinning and hair loss can significantly decrease quality of life. Dr. Alison Bruce breaks down different types of hair loss, who’s a candidate, and new therapies on the horizon. Dr. Shane Shapiro will discuss the application of regenerative medicine to this condition and how platelet rich plasma has demonstrated efficacy at regrowing hair. 

Deeper Dive: 

• A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women doi: 10.1097/DSS.0000000000002168 

Episode transcript: https://mcdn.podbean.com/mf/web/d545pv/Ep_185-Regenerative_Medicine_Takes_on_Hair_Loss.pdf

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 48: Answers from the Lab - Neutralizing Antibody Assay, Explained

This episode is shared from Answers from the Lab and was originally published June 30, 2020. 

Guest: John R. Mills, Ph.D. 

Host: Bobbi S. Pritt, M.D. (@ParasiteGal) 

John Mills, Ph.D., is the co-director of the Neuroimmunology Laboratory at Mayo Clinic and the scientist who oversaw the development and validation of the new neutralizing antibody assay. Today he joins us to explain what the neutralizing antibody assay is, why it is different than other COVID-19 tests, and the science and innovation behind these efforts. 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Answers from the Lab: Future of COVID-19 Laboratory Testing

This episode is shared from Answers from the Lab and was originally published June 25, 2020. 

Guest: William G. Morice, II M.D., Ph.D. (@moricemdphd) 

Host: Bobbi S. Pritt, M.D. (@ParasiteGal) 

William Morice, II, M.D., Ph.D., Chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic and President of Mayo Clinic Laboratories, joins the Answers from the Lab podcast for his weekly leadership update. In this episode, Dr. Morice discusses the future of testing for COVID-19, predicting who would be at the highest risk for severe disease, and challenges with existing diagnostics. 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 

Sorting Out Knee Pain and Treatment Opportunities

Guest: Daniel B. Saris, M.D., Ph.D. (@sarisnl) 

Host: Darryl S. Chutka, M.D. (@ChutkaMD) 

With over 12 million outpatient visits annually in association with knee pain, it’s a common presentation in primary care. Dr. Daniel Saris discusses what questions we should be asking our patients, when to order imaging studies, and the common causes of pain broken down by age demographic. He’ll also discuss stem cell therapy, who is a good candidate, and who isn’t. 

Episode transcript: https://mcdn.podbean.com/mf/web/cjj292/Ep_183-Sorting_Out_Knee_Pain_and_Treatment_Opportunities.pdf

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 47: Answers from the Lab - Serology Testing for COVID-19

This episode is shared from Answers from the Lab and was originally published June 16, 2020. 

Guest: Elitza Theel, Ph.D. (@ElliTheelPhD) 

Host: Bobbi S. Pritt, M.D. (@ParasiteGal) 

Elitza Theel, Ph.D., Laboratory Director of the Infectious Diseases Serology Laboratory at Mayo Clinic, led the efforts to evaluate and implement the serologic antibody test for COVID-19. She gives an overview of Mayo Clinic’s COVID-19 antibody test, as well as the role of antibody testing during the pandemic, and how sensitivity, specificity, and prevalence play a large role in the positive predictive value of a test. 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd 

COVID-19 Miniseries Episode 46: Physician Leaders and the Science of Health Care Delivery

This episode was recorded August 6, 2020. 

To claim credit visit: https://ce.mayo.edu/covid19podcast 

Guest: Lisa A. McGee, M.D. 

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

What are population centered care and health? How do we best use rationed resources within our health care system to most effectively meet these needs? Dr. Lisa McGee discusses the Science of Health Care Delivery,  the impact mass media messages have had on the current COVID-19 pandemic, and how we can use the information we have about population centered health to address key influential components of SARS-CoV-2’s continual spread. 

Suggested Readings: 

1. The effect of public health measures on the 1918 influenza pandemic in U.S. cities 
   https://doi.org/10.1073/pnas.0611071104 
2. Public health interventions and epidemic intensity during the 1918 influenza pandemic 
   https://doi.org/10.1073/pnas.0610941104 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 45: There Is No Win-Win

This episode was recorded on June 26, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast 

Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh) 

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Novel viruses causing outbreaks tend to do one of three things: disappear completely, become endemic in certain areas, or roll through populations with ongoing transmission until herd immunity is achieved or an effective vaccine is developed. Dr. Pritish Tosh states, “If natural infection doesn’t cause long-lasting protective immunity or the vaccines don’t do the same, this thing could be with us for a long time.” Take a walk through the past 100 years of pandemics as Dr. Tosh draws comparisons and lessons learned. 

The Economist - The Grim Calculus 
https://www.economist.com/leaders/2020/04/02/covid-19-presents-stark-choices-between-life-death-and-the-economy 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 44: Supply Chain Vulnerability - Why Don’t We Have Enough PPE?

This episode was recorded on June 26, 2020. 

To claim credit visit: https://ce.mayo.edu/covid19podcast 

Guest:  Pritish K. Tosh, M.D. (@DrPritishTosh) 

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

“Everybody has a plan until they get punched in the mouth.” - Mike Tyson 

Thin margins and economies of scale help lower costs but can create significant vulnerabilities. Often calculations of lives lost in the event of a shortage or costs to stockpile may not be factored in when sourcing supplies. Healthcare supply chain practices over decades have lead to significant weak points in our supply chains for some vital materials and we often have no view of this until it’s too late. 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 43: Healthcare Disparities and Systemic Racism

This episode was recorded June 25, 2020. 

To claim credit visit: https://ce.mayo.edu/covid19podcast 

Guest:  Kenneth G. Poole, Jr. M.D., M.B.A. (@KPooleMD) 

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Black, Latino, and Native American populations have been disproportionately affected by COVID-19. Underlying health inequities have been a major contributor. Dr. Kenneth Poole discusses social determinants of health and how these combined with systemic racism, predating COVID-19, laid the groundwork for the suffering we’re seeing unfold. What can we do to address it effectively? 

COVID-19 and African Americans - Clyde Yancy 
https://jamanetwork.com/journals/jama/fullarticle/2764789 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 42: The Impact of Care Disruption for Patients with Non-Emergent Needs

This episode was recorded May 19, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:  Sidna M. Tulledge-Scheitel, M.D., M.P.H.

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

The COVID-19 pandemic has caused waves of care disruption for people around the world. What patient populations have faced unique risks? What signs of impact from the temporary restriction of medical outpatients services are we seeing? Dr. Tulledge-Scheitel shares what’s being seen at Mayo Clinic, what she anticipates we’ll be seeing in the coming months, and what she’d do should this need arise again in the future.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 41: Breaking Down the Impact of Smoking in COVID-19 Part 2

This episode was recorded June 17, 2020. 

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:   J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D.

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Is the act of smoking a risk factor for transmission? Does nicotine protect against severe COVID-19? Dr. Hays and Dr. Vassallo discuss what is currently known about the risks of smoking in regard to COVID-19 and treatment of patients who smoke, during the pandemic.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 40: Breaking Down the Impact of Smoking in COVID-19 Part 1

This episode was recorded June 17, 2020. 

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:  J. Taylor Hays, M.D. (@jtaylorhays), Robert Vassallo, M.D.

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Is smoking a risk factor for severe disease in COVID-19? How accurate is the documentation of smoking in COVID-19 cohorts currently published? What role should a smoking history play in the prognosis and management of COVID-19? Drs. Hays and Vassallo discuss the prevalence of smoking worldwide, the impact of documentation, and the role smoking may play in COVID-19.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 38: The Enduring Power of Compassion

This episode was recorded on May 13, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:  David J. Rosenman, M.D. (@davidrosenman)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

“At a time when most of the world in one way or another is suffering, it seems relevant to talk about ways to relieve some of that suffering and to help.” Studies have shown that patients value empathy over sympathy, and compassion over empathy. While measures to protect ourselves and understand the spread of COVID-19 and the clinical presentation of the disease are underway, the inconsistency of information across sources brings greater uncertainty for our patients and at times ourselves. 

Dr. Rosenman discusses what compassion is and the importance of compassion as a tool to help us and our patients, feel better mentally and physically. He recommends practicing self-compassion and will step through the practices of self-kindness, common humanity, and mindfulness. 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 37: Movement is Medicine

This episode was recorded on May 28, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest:  Edward R. Laskowski, M.D. (@DrEdSportsMed)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

The world was already facing an epidemic of inactivity prior to the emergence and spread of SARS-CoV-2. Some have been able to focus more on self-care and fitness while under stay-at-home measures but with the necessity of social distancing and the widespread closure of fitness centers others have encountered significant challenges. What is the real cost of inactivity? Whether it’s the “Quarantine 15” or the psychological effects of being isolated in a world constantly changing, Dr. Laskowski shares one of the most effective treatments you can recommend to your patients.

Deeper Dive:

• Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging
  https://doi.org/10.4065/mcp.2011.0252
• Strength training: How-to video collection
  https://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/strength-training/art-20046031
• Physical Activity Guidelines for Americans
  https://www.hhs.gov/fitness/be-active/physical-activity-guidelines-for-americans/index.html

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Mayo Clinic Q & A - Medical Education During the COVID-19 Pandemic

This episode is shared from Mayo Clinic Q&A and was recorded in June, 2020.

Guest:  Alexandra P. Wolanskyj-Spinner, M.D. (@apw01)

Host: Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)

Across the world, one of the biggest changes forced by the COVID-19 pandemic is in the field of education. Programs from kindergarten through postsecondary have rapidly moved to a distance learning model. Online and remote instruction has its own unique challenges, and has required students and educators to be creative to stay connected.

On the Mayo Clinic Q&A podcast, Dr. Alexandra Wolanskyj-Spinner, senior associate dean for student affairs at the Mayo Clinic Alix School of Medicine in Minnesota, discusses medical education during the COVID-19 pandemic.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 36: A Comprehensive Update on COVID-19

This episode was recorded on June 5, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest: Raymund R. Razonable, M.D. (@RazonableMD)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Up to about 50% of people infected with SARS-CoV-2 are asymptomatic spreaders. About 80% of those who are symptomatic, developing COVID-19, have mild disease displaying dry cough, fever, and fatigue. The resulting 20% of symptomatic patients accounts for those who develop progressive respiratory distress and sometimes multi-organ failure, among other complications. We’re learning more about anosmia, cardiac injury, and “COVID-toes.” What’s known about COVID-19 and SARS-CoV-2 continues to evolve. Dr. Raymund Razonable walks through a recently published update on the management of COVID-19. 

Time Stamps:
1:18 - New signs and symptoms of COVID-19.
3:30 - Testing characteristics (sensitivity, specificity, and indications)  of the molecular and serologic testing for SARS-CoV-2
6:22 - Risk factors and the prediction of disease progression for patients hospitalized with COVID-19
9:28 - Hyper-inflammatory syndrome and progression to multi-system organ failure syndrome
10:45 - Multisystem inflammatory syndrome in children (MIS-C)
11:22 - Cardiac complications - 3 factors
12:50 - Diagnosis and treatment of co-infection in hospitalized patients (COVID-19 and flu, COVID-19 and pneumonia)
16:31 - Evidence-based treatment based on the 3 phases of COVID-19 viremic phase, pneumonic phase, hyperinflammation phase
18:06 - Remdesivir update
21:00 - Hydroxychloroquine update
23:25 - Favipiravir and lopinavir-ritonavir update
23:53 - Treatment of the hyperinflammatory phase (sarilumab, tocilizumab, lenzilumab, anakinra,)
27:13 - Convalescent plasma
28:04 - Discharge and social determinants of health
33:40 - Telehealth and remote monitoring
35:40 - Health disparities and telehealth
37:47 - What’s the next development Infectious Disease specialists are looking for in relation to the COVID-19 pandemic?

See the article here:
A Collaborative Multidisciplinary Approach to the Management of Coronavirus Disease-19 in the Hospital Setting https://doi.org/10.1016/j.mayocp.2020.05.010

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 35: Alternative Ventilation Strategies

This episode was recorded on May 12, 2020.

Guest:  James E. Baker, R.R.T., L.R.T. &  Steven R. Holets, R.R.T., L.R.T.

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

What are some alternative ventilation strategies we can use to treat patients with COVID-19? James Baker, R.R.T., L.R.T. and Steve Holets, R.R.T., L.R.T. discuss individualizing care, limitations based on device design, and supply chain concerns.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 34: Multi-System Inflammatory Syndrome (MIS-C) in Pediatric Patients

This episode was recorded on May 27, 2020.

Guest:  Nipunie S. Rajapakse, M.D., M.P.H. (@nrajapakseMD)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Patients under 21 who present with fever, lab evidence of inflammation, multisystem involvement, and recent or current SARS-CoV-2 infection fall under the case definition for multisystem inflammatory syndrome. They commonly present with persistent fever and gastrointestinal symptoms and concerningly, shock. Why are we seeing disproportionate rates in children of racial and ethnic minorities? Dr. Nipunie Rajapaske concisely covers what’s known about this syndrome and the data supporting its emergence as a post-infection complication.

CDC Health Advisory on Multisystem Inflammatory Syndrome in Children (MIS-C)
https://emergency.cdc.gov/han/2020/han00432.asp

An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study
https://doi.org/10.1016/S0140-6736(20)31103-X

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 33: Mayo Clinic Q&A - COVID-19 Transmission Risks and Precautions

This episode is shared from Mayo Clinic Q&A and was recorded on May 26, 2020.

Guest:  Gregory A. Poland, M.D. (@drgregpoland)

Host: Halena M. Gazelka, M.D. (@hmgazelkamd)

According to the Centers for Disease Control and Prevention, the most common mode of transmission for COVID-19 is through close contact from person to person. While it is possible that someone can get COVID-19 by touching a surface or object that has the virus on it and then touching their own mouth, nose or possibly their eyes, this isn’t thought to be the main way the virus spreads.

On the Mayo Clinic Q&A podcast, Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic’s Vaccine Research Group, discusses virus transmission and steps to take to keep yourself safe.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 32: The Fierce Urgency of Now - Pursuing a Safe and Efficacious Vaccine

This episode was recorded May 22, 2020

To claim credit visit: https://ce.mayo.edu/covid19podcast

 

Guest: Gregory A. Poland, M.D. (@drgregpoland)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

SARS-CoV-2, as an RNA virus, has marked capacity for mutation and recombination events. How do we build an efficacious and safe vaccine against it? How could we safely speed up development? Is a vaccine neutralizing the spike protein enough? Dr. Greg Poland returns to give you an update from the front lines of research on vaccine development and ongoing clinical trials.

Dr. Poland’s Editorial:
Tortoises, hares, and vaccines: A cautionary note for SARS-CoV-2 vaccine development
https://doi.org/10.1016/j.vaccine.2020.04.073

 

'I Have A Dream' Speech, In Its Entirety

https://www.npr.org/2010/01/18/122701268/i-have-a-dream-speech-in-its-entirety

Our 'Fierce Urgency of Now' -  Secretary Kathleen Sebelius
https://obamawhitehouse.archives.gov/blog/2013/08/26/our-fierce-urgency-now

King Legacy: 'Fierce Urgency of Now' Exists Today - Terri Moon Cronk
https://www.defense.gov/Explore/Features/Story/Article/2059480/king-legacy-fierce-urgency-of-now-exists-today/

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 31: The Safety of Convalescent Plasma

This episode was recorded May 21, 2020

Visit the program site here:  https://www.uscovidplasma.org

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest: Michael J. Joyner, M.D. (@DrMJoyner)

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

Convalescent plasma as a passive immunity strategy is not new. What nuances apply for it’s application to treating COVID-19? Is it safe? Is it efficacious? Dr. Michael Joyner, Principal Investigator for Expanded Access to Convalescent Plasma for the Treatment of Patients with COVID-19, discusses what’s known about this treatment option, information that’s currently being gathered, and how you can get involved.

AABB Coronavirus Resources: http://www.aabb.org/advocacy/regulatorygovernment/Pages/AABB-Coronavirus-Resources.aspx

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 30: Mayo Clinic Q&A - Addressing Health Disparities Amplified by COVID-19

This episode is shared from Mayo Clinic Q&A and was recorded in May 2020.

Guest: Irene G. Sia, M.D.; Mark L. Wieland, M.D.

Host:  Sanjeev (Sanj) Kakar, M.D. (@sanjkakar)

Minorities are being affected disproportionately by the COVID-19 pandemic. Early data shows that African Americans and other U.S. ethnic minorities have contracted COVID-19 at a higher rate and experience greater sickness and a higher death rate than other Americans. 

On the Mayo Clinic Q&A podcast, Dr. Irene Sia, a Mayo Clinic infectious diseases expert, and Dr. Mark Wieland, a Mayo Clinic community internal medicine physician, discuss ethnic disparities and COVID-19, including research being done with the Rochester Healthy Community Partnership.

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 29: Lab Medicine Rounds - Understanding COVID-Associated Coagulopathy

This episode is shared from Lab Medicine Rounds  and was recorded May 1, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest: Ariela L. Marshall, M.D. (@AMarshallMD)

Host: Justin D. Kreuter, M.D. (@KreuterMD)

What is COVID-Associated coagulopathy? Why is it so important to recognize early on? How does it differ from the typical disseminated intravascular coagulation (DIC) picture? Dr. Ariela Marshall details the lab patterns, implications for our patients, and what testing should be evaluated on patients being treated for COVID-19 and when.

Time Stamps:

00:00 Podcast Intro

00:40 What is COVID-associated coagulopathy and why is it important to recognize this?

02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice?

04:30 Is there recommended testing for COVID-associated coagulopathy?

06:30 Can you explain what the soluble fibrin monomer test is?

08:09 How is COVID-associated coagulopathy managed in terms of prophylactic anticoagulation, therapeutic anticoagulation, and prophylactic transfusion?

14:23 What are a few lessons that you have learned during this pandemic so far?

Resources:

1. F.A. Klok, M.J.H.A. Kruip, N.J.M. van der Meer, et al., Incidence of thrombotic complications in critically ill ICU patients with COVID-19,Thrombosis Research (2020) https://doi.org/10.1016/j.thromres.2020.04.013 
2. Thachil J, Tang N, Gando S, Falanga A, Cattaneo M...Iba T, et al. ISTH interim guidance on recognition and management of coagulopathy in COVID‐19 https://doi.org/10.1111/jth.14810

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

ISTH COVID-19 Resources

Subscribe to Lab Medicine Rounds here: https://news.mayocliniclabs.com/podcast/lab-medicine-rounds/

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

COVID-19 Miniseries Episode 28: Reflections on Telehealth and Teaching

This episode was recorded April 30, 2020.

To claim credit visit: https://ce.mayo.edu/covid19podcast

Guest: Christopher A. Aakre, M.D.

Host: Amit K. Ghosh, M.D., M.B.A. (@AmitGhosh006) 

How do you approach planning for telehealth visits? Dr. Chris Aakre discusses preparing by considering How am I going to assess this concern by video? What are you looking for? What are you hoping to see there? How are you best going to be able to instruct the patient? 

AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19

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