Episodes

Tuesday Aug 10, 2021
Working from the Ground Up to Impact Gender Disparities in COVID-19
Tuesday Aug 10, 2021
Tuesday Aug 10, 2021
Guest: Carol L. Kuhle, D.O., M.P.H. (@clkejd)
Host: Anjali Bhagra, M.D. (@anjalibhagramd)
Anjali Bhagra, M.D., and Carol L. Kuhle, D.O., M.P.H., discuss the narrative they recently published in Mayo Clinic Proceedings, which outlines and highlights the further widening of preexisting gender disparities in response to the COVID-19 pandemic. What can we do to identify and mitigate these issues?
Additional resources:
- Nordhues, HC. Bhagra, A. Stroud, NN. Vencill, JA. Kuhle, CL. COVID-19 gender disparities and mitigation recommendations: a narrative review. Mayo Clin Proc. 2021 April 20; 96(7): 1907-1920. doi: https://doi.org/10.1016/j.mayocp.2021.04.009
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Friday Aug 06, 2021
Mayo Clinic Q&A: The COVID-19 Delta Variant has Changed Everything
Friday Aug 06, 2021
Friday Aug 06, 2021
This episode is shared from Mayo Clinic Q&A and was recorded August, 2021
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
A fourth COVID-19 surge is blanketing the U.S., and the delta variant is the culprit.
"Where did this delta variant come from? It came from unvaccinated people getting infected in large numbers allowing the virus to continue mutating," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.
In the past, a person with COVID-19 might infect two to four people. But with the delta variant, one person can infect nine people, according to Dr. Poland. He says if you want to protect yourself and your family, wear a mask, especially indoors, and get vaccinated with an appropriate series of one of the COVID-19 vaccines.
"These are the most studied vaccines in the history of the world," Dr. Poland emphasizes. "There have never been this many people who have received this many doses of vaccines during this amount of time with as much scrutiny as these COVID-19 vaccines have had."
In this Mayo Clinic Q&A podcast, Dr. Poland answers questions about a person's waning immunity and the likelihood of COVID-19 booster shots. He also explains the two phases of immunity and goes into detail about the extensive Federal Drug Administration license approval process for COVID-19 vaccines.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Aug 03, 2021
Will We Be Replaced by Computers? Artificial Intelligence and Medicine
Tuesday Aug 03, 2021
Tuesday Aug 03, 2021
Guest: Steve G. Peters, M.D.
Host: Sanjeev Kakar, M.D. (@sanjkakar)
No doubt you’ve heard the term “artificial intelligence,” by now; but what is it exactly? How can medicine use AI to improve patient care and outcomes? Will it one day replace doctors’ years of training? Steve Peters, M.D. a pulmonary and critical care medicine consultant, with a special interest in AI, at Mayo Clinic’s Rochester campus. Dr. Peters will help us take a look into the not-so-distant future as we explore AI and its role in medicine.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Friday Jul 30, 2021
Mayo Clinic Q&A: Stopping the Spiral of the COVID-19 Delta Variant
Friday Jul 30, 2021
Friday Jul 30, 2021
This episode is shared from Mayo Clinic Q&A and was recorded July, 2021
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
Transmission of the COVID-19 delta variant is increasing.
"We're in this constant spiral, right now,” says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.
“The delta variant is so highly contagious,” he says. “The number of delta viral particles in the upper respiratory system is reportedly 1,000 times higher than with the original COVID-19 virus. If we can't find ways to get people vaccinated, we are going to be in a world of hurt. And I don't say that to be alarmist. I say it to be a realist, based on what’s happening right in front of us.”
But Dr. Poland says the spiral can be stopped by getting higher rates of immunization.
"Getting a COVID-19 vaccine will prevent the development of worse and worse variants. It will prevent severe cases of hospitalization and death, even in the face of a variant,” he says. "The alternative is to lose another 600,000-plus Americans. Only this time it will, unfortunately, involve younger people."
Dr. Poland explains further, "Every time somebody gets infected with the delta variant, there's the opportunity for that virus to mutate and transmit to other people," says Dr. Poland. "This means that immunization rates to control herd immunity will probably have to be in the 85% to 95% range."
In this Mayo Clinic Q&A podcast, Dr. Poland continues to talk about the delta variant, breakthrough infections, booster shots and much more.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jul 27, 2021
What’s That Sound? Maybe It’s Stridor
Tuesday Jul 27, 2021
Tuesday Jul 27, 2021
Guest: Shelagh A. Cofer, M.D. (@ShelaghCoferMD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Stridor is a musical sound due to disrupted airflow in an individual’s airway. In many instances it’s due to a benign cause but it can also represent a serious problem, possibly even life-threatening. In today’s podcast, we’ll learn about the various causes of stridor and when we need to be concerned that it represents a serious health issue. Our guest for this podcast is Dr. Shelagh Cofer, a pediatric otolaryngology specialist at the Mayo Clinic. We’ll discuss how stridor differs from wheezing, the most common causes of stridor in both children and adults and what symptoms we should be watching for that might suggest a serious cause for stridor. We’ll also cover the evaluation of patients with stridor, which imaging studies may be helpful and when an ENT consultation is warranted.
Specific topics:
- Definition of stridor
- Difference between stridor, stertor, and wheezing
- Most common causes of stridor in both children and adults
- Croup as a form of stridor
- Important questions we should be asking our patients about stridor to identify those at risk for airway obstruction – including the SPECS-R mnemonic
- Tests and imaging studies which may be helpful in the evaluation of a patient with stridor
- Treatments for the more common causes of stridor
Additional resources:
- Zoumalan, R; Maddalozzo, J; Holinger, LD. Etiology of stridor in infants. Ann Otol Rhinol Laryngol. 2007; 116(5):329-334. doi: 10.1.1896.429 https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.896.429&rep=rep1&type=pdf
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jul 22, 2021
Mayo Clinic Q&A: On the Verge of Predicted COVID-19 Surge with Delta Variant
Thursday Jul 22, 2021
Thursday Jul 22, 2021
This episode is shared from Mayo Clinic Q&A and was recorded July, 2021
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
The delta variant is being blamed for hot spots in the U.S. where cases of COVID-19 are on the rise. These hot spots account for most cases in the U.S. They are also the geographical areas that tend to have the lowest vaccination rates.
"It's no surprise that the two go together," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.
"This (delta variant) is the bad actor that we predicted it would be," adds Dr. Poland. "Our seven-day average is getting up to 19,000 cases a day in the U.S. We were down to 3,000. So we're starting to see, just as we predicted, a surge as people took masks off and as restrictions were lifted before we had achieved high rates of immunization."
In this Mayo Clinic Q&A podcast, Dr. Poland expands on how the highly transmissible delta variant continues to spread. He also talks about the possibility of COVID-19 vaccine boosters, explains how the Vaccine Adverse Event Reporting System works, and much more as he answers listener questions.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jul 20, 2021
Multidisciplinary Approach to Pelvic Pain
Tuesday Jul 20, 2021
Tuesday Jul 20, 2021
Guest: Isabel C. Green, M.D.
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Pelvic pain can be challenging. It can have a variety of presenting symptoms since it can originate from a variety of organ systems. When pelvic pain becomes chronic, it becomes even more challenging. It’s associated with significant direct medical costs as well as indirect costs as it frequently results in work absenteeism. Patients with chronic pelvic pain are often initially evaluated by primary care providers, but referral to specialists is quite common. Due to the variety of symptoms associated with chronic pelvic pain, multiple specialties often are asked to evaluate these patients. This frequently results in patients being passed back and forth between various medical specialties. It therefore becomes important for primary care providers to become comfortable evaluating and managing patients with pelvic pain. Our guest for this podcast is Dr. Isabel Green, a physician from the Department of Obstetrics and Gynecology at the Mayo Clinic. We’ll discuss how to effectively evaluate patients with pelvic pain, “red flag symptoms” to watch for, useful laboratory tests to order, and common imaging studies which can be helpful in establishing a cause for the pain. We’ll also discuss the benefits of a multi-disciplinary approach to pelvic pain.
Specific topics:
- Categorization of pelvic pain
- Appropriate evaluation of pelvic pain including the clinical history, physical exam, laboratory tests and imaging studies
- Relationship of chronic pelvic pain with other symptoms such as anxiety, depression, insomnia, and work/relationship issues
- Chronic pelvic pain representing a form of centralized pain
- Advantages of a multi-disciplinary approach to evaluating and managing chronic pelvic pain
Additional resources:
- Chronic pelvic pain: ACOG practice bulletin, number 218. Obstet Gynecol. 2020 Mar; 135(3):e98-e109. doi: 1097/AOG.0000000000003716.
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jul 13, 2021
Identifying and Treating Urinary Urge Incontinence
Tuesday Jul 13, 2021
Tuesday Jul 13, 2021
Guest: Brian J. Linder, M.D. (@brianjlinder)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Patients rarely mention urinary incontinence to us as a problem as many assume it’s a normal change of aging. However, it’s a major quality-of-life issue. Many with incontinence are reluctant to go out in public and those who do, usually know the location of all the nearby restrooms. Yet, with proper evaluation and treatment, essentially all patients can be helped, and in many cases, they can be cured. In this podcast, we’ll discuss urgency urinary incontinence, one of the most common forms of incontinence. We’ll cover the questions you should ask your patients to make a diagnosis, what evaluation you should do, and what treatment options are available. Our guest for this topic is Dr. Brian Linder, a urologist at the Mayo Clinic.
Specific topics:
- The various types of urinary incontinence
- Important questions to ask patients to make a diagnosis
- Effective use of a voiding diary
- Physical exam recommendations
- Helpful laboratory tests
- When urodynamic studies are indicated
- Non-pharmacologic treatment options
- Medications useful in treating urgency incontinence
- Treatment options for the refractory patient
Additional resource:
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Wednesday Jul 07, 2021
Mayo Clinic Q&A: Summer Travel and People Not in Your Bubble During COVID-19 Pandemic
Wednesday Jul 07, 2021
Wednesday Jul 07, 2021
This episode is shared from Mayo Clinic Q&A and was recorded June, 2021
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
"The reason we have the COVID-19 delta variant, the reason we have the delta plus variant is because of unimmunized people who get infected," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. He adds that 99.2% of the recorded COVID-19 deaths in the U.S. are in people not vaccinated against the virus.
This is why he cautions folks who may be traveling this Fourth of July holiday and throughout the summer.
"You don't know what variants people are carrying, how symptomatic they are, the health of their immune system, or if they've been vaccinated," says Dr. Poland. "When you are around groups of people indoors that are not in your bubble, so to speak, I think you should still wear a proper mask."
In this Mayo Clinic Q&A podcast, Dr. Poland explains why, even if you are fully vaccinated for COVID-19, you should still consider being masked in some situations. He also discusses breakthrough infections in certain subpopulations, and what that may mean for needing booster shots.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jul 06, 2021
Postural Orthostatic Tachycardia Syndrome (POTS) in Adult Patients
Tuesday Jul 06, 2021
Tuesday Jul 06, 2021
Guest: Jeremy K. Cutsforth-Gregory, M.D. (@JCGneuro)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Postural Orthostatic Tachycardia Syndrome, or POTS, is a medical condition manifested by tachycardia that occurs after standing or prolonged sitting and is often associated with symptoms such as dizziness, fatigue, and occasionally syncope. POTS can be difficult to diagnose as patients often present with a variety of vague, and what seem like unrelated, symptoms. Management of patients with POTS can be equally difficult as there’s no one treatment which is effective in all patients. However, patients with POTS often have typical symptoms and objective findings on physical exam. Once a diagnosis is made, effective treatment is available and many patients with POTS can be helped with non-pharmacologic therapy. To help us understand POTS and its management, we’ll speak with Dr. Jeremy Cutsforth-Gregory, a neurologist at the Mayo Clinic. We’ll discuss the proposed theories regarding the cause of POTS, the different types of POTS, pathologic findings in patients with POTS, and the management of patient with POTS.
Specific Topics:
- Typical symptoms of POTS
- Risk factors for POTS
- Theories regarding the cause of POTS
- Description of the varieties of POTS
- How to diagnose POTS
- Pathologic and pharmacologic abnormalities related to POTS
- Management of patients with POTS
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jul 01, 2021
Regenerative Medicine Edition Ep.10: FDA Regulatory Process and Clinical Trials
Thursday Jul 01, 2021
Thursday Jul 01, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Drew M. Witter, CCRP
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
“Stem Cell Clinics” throughout the U.S. promote stem cell therapy for a variety of health conditions including osteoarthritis, autism, macular degeneration, Parkinson’s Disease, Alzheimer’s Disease and most recently COVID-19 infections. How can our patients be assured that the regenerative medicine therapy effectively treats their health condition and the products they receive are safe? In this podcast, we discuss regulations regarding regenerative medicine, the process of obtaining FDA-approval and which regenerative medicine therapies are FDA-approved. Our guest will be Drew Witter, a Program Manager from the Office of Research and Regulatory Support at the Mayo Clinic.
Specific topics discussed:
- Process of taking regenerative medicine from the research lab to the clinical practice
- How regulators ensure the safety and effectiveness of regenerative therapies
- The process of acquiring FDA-approval
- Regenerative medicine therapies that are FDA-approved
- How patients and clinicians learn of FDA-regulated regenerative medicine clinical trials
Additional resources:
- Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials
- U.S. National Library of Medicine: https://www.clinicaltrials.gov/
- Center Watch: https://www.centerwatch.com/
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jun 29, 2021
Primary Care Management of the Post-Prostate Cancer Patient
Tuesday Jun 29, 2021
Tuesday Jun 29, 2021
Guest: Matthew K. Tollefson, M.D. (@MattTollefsonMD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Other than skin cancer, prostate cancer is the most common cancer in men in the United States and will affect 1 in every 6 men 65 years and older. Fortunately, when detected early, it is very treatable. Long-term follow-up of patients with treated prostate cancer is usually performed by primary care providers. How often should these patients be seen? How much of an exam is recommended? Which tests should be ordered? When are imaging tests indicated and which studies are the most helpful? This podcast will address these questions and more as we discuss the primary care management of the post-prostate cancer patient with Dr. Matthew Tollefson, a urologist from the Mayo Clinic.
Specific topics discussed:
- Current treatment options for prostate cancer
- Determinants for choosing one of the treatment options for prostate cancer
- When and how often patients should receive follow-up for prostate cancer
- Laboratory tests recommended for the follow-up of prostate cancer patients
- When a detectable PSA is concerning following prostate cancer treatment
- Imaging studies recommended for following prostate cancer patients and when they are indicated
- Treatment options for recurrent prostate cancer
- Future treatment options for prostate cancer which have potential
Additional resources:
- https://www.auanet.org/guidelines/advanced-prostate-cancer
- https://www.mayoclinic.org/diseases-conditions/prostate-cancer/symptoms-causes/syc-20353087
- https://www.mayoclinic.org/medical-professionals/urology
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Friday Jun 25, 2021
Friday Jun 25, 2021
This episode is shared from Mayo Clinic Q&A and was recorded June 21, 2021
To claim credit visit: https://ce.mayo.edu/covid19podcast
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
Summer and fall are going to be a dangerous time for people in the U.S. who have not been vaccinated for COVID-19, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.
"I really think this exponential rise in the number of sequences that are delta must be taken seriously," says Dr. Poland. "We are seeing a surge again, in hospitalizations in the UK, because of the delta variant in people who have not been vaccinated or who only got one dose of vaccine. This is a really critical message for the public to hear because in the U.S. we are stalled in vaccination rates."
In this Mayo Clinic Q&A podcast, Dr. Poland talks more about a possible COVID-19 surge and being emotionally ready for the pandemic to be over. He also answers listener questions about COVID-19 reinfection, the latest on antiviral development for COVID-19, and the latest news about COVID-19 vaccines affecting menstrual cycles and sperm quality.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jun 24, 2021
Regenerative Medicine Edition Ep.9: Cardiac Regenerative Therapies
Thursday Jun 24, 2021
Thursday Jun 24, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Atta Behfar, M.D., Ph.D. (@AttaBehfar)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Traditional treatment of cardiac disease, especially advanced congestive heart failure has been limited. Transplantation has potential for benefit; however, organ shortage remains a barrier. It’s anticipated that regenerative medicine will help solve this unmet need with new treatment options to repair damaged heart tissue. This podcast will discuss regenerative medicine for cardiovascular disease with Dr. Atta Behfar, a Mayo Clinic cardiologist with expertise in advanced heart failure and transplantation. We’ll review the progress made in regenerative medicine in management of cardiovascular disease, what treatment options are currently available and the potential treatment options which will become available in the future.
Specific topics discussed:
- Regenerative potential of the cardiovascular system
- Current challenges in management of patients with cardiovascular disease
- Progress in regenerative medicine for the cardiovascular system
- Limitations in regenerative cardiac therapy using regenerative medicine
- Future potential for regenerative medicine treatment of cardiovascular disease
- Patients who are candidates for cardiac regenerative therapies
Additional resources:
- Clinical Trials available at Mayo Clinic through the Center for Regenerative Medicine: https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/patient-care/clinical-trials
- U.S. National Library of Medicine: https://www.clinicaltrials.gov/
- Center Watch: https://www.centerwatch.com/
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Wednesday Jun 23, 2021
Wednesday Jun 23, 2021
This episode is shared from Mayo Clinic Q&A and was recorded June 14, 2021
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices is holding an emergency COVID-19 meeting this week to discuss COVID-19 vaccine safety as it relates to news that young people may develop myocarditis after receiving a second dose of a messenger RNA COVID-19 vaccine.
Myocarditis, which is an inflammation of the heart muscle, is usually caused by a viral infection. But it can result from a reaction to a drug or be part of a more general inflammatory condition. Signs and symptoms include chest pain, fatigue, shortness of breath and arrhythmias.
"There have been about 789 cases reported," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "And that can happen for a whole variety of reasons."
In this Mayo Clinic Q&A podcast, Dr. Poland details the concerns about the myocarditis reports. He also discusses the latest news on the COVID-19 delta variant, and he explains what scientists are calling the "two-track pandemic."
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jun 22, 2021
The Sobering Statistics of Alcohol Use Disorder
Tuesday Jun 22, 2021
Tuesday Jun 22, 2021
Guest: Terry D. Schneekloth, M.D.
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
According to the 2019 National Survey on Drug Use and Health, nearly 26% of individuals 18 and older reported that they engaged in binge drinking and slightly over 6% engaged in heavy alcohol use within the past month. Binge drinkers were 70 to 90 times more likely to have an alcohol-related emergency department visit. Based on their data from this study, they estimated that nearly 15 million people ages 12 and older had alcohol use disorder. It’s also known that those with alcohol use disorder commonly seek care from primary care providers for alcohol-related medical problems. Our guest for this podcast is Terry Schneekloth, M.D., a psychiatrist and addiction specialist at Mayo Clinic.
Specific topics discussed:
- Definition of alcohol use disorder
- Risk factors for alcohol use disorder
- Role of genetics
- Questions primary care providers should ask to explore the possibility of an alcohol use disorder in patients
- Physical exam or lab findings which could suggest an alcohol use disorder
- Available treatment options and their alcohol use disorder effectiveness
Additional Resources:
- World Health Organization (WHO). Alcohol Use Disorders Identification Test (AUDIT). 2001 November 18; https://www.who.int/publications/i/item/audit-the-alcohol-use-disorders-identification-test-guidelines-for-use-in-primary-health-care
- National Institute on Alcohol Abuse and Alcoholism (NIAAA). National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study: https://www.niaaa.nih.gov/research/nesarc-iii
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jun 17, 2021
Regenerative Medicine Edition Ep.8: Neuroregenerative Therapies
Thursday Jun 17, 2021
Thursday Jun 17, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Nathan Staff, M.D. (@NathanStaffMD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
The cells in our nervous system are extremely specialized, especially those in the brain. Unfortunately, nervous tissue does not have a great potential to regain function once it is lost. Exciting research is being done in the field of neuro-regenerative medicine which will give hope for improvement to those with chronic neurodegenerative disease or nerve damage from injury. Dr. Nathan Staff, a Mayo Clinic neurologist, joins us regarding the challenges with the current management of chronic neurodegenerative diseases and the future potential for treating such conditions as Parkinson’s Disease, Alzheimer’s Disease, ALS and other neurodegenerative disease with regenerative medicine therapies.
Specific topics discussed:
- Current research in regenerative medicine treatment for chronic neurodegenerative disease
- Currently used regenerative medicine in neurologic conditions
- New treatment options on the horizon for chronic neurodegenerative disease using regenerative medicine therapy
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jun 15, 2021
The Agony of Da Feet - Assessing Foot and Ankle Pain and Injury
Tuesday Jun 15, 2021
Tuesday Jun 15, 2021
Guest: Daniel B. Ryssman, M.D.
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Generally, we take our feet for granted. It’s not unusual for a person to take 8- to 10-thousand steps per day. That translates to over 115,000 miles in a lifetime. By the time we reach 70 years old, the average person will have walked the equivalent of 4 times around the globe. Yet, we stop taking our feet for granted when they hurt, and it’s estimated that 75% of Americans will experience foot problems of varying degrees of severity during their lifetime. In this podcast, we’ll discuss foot and ankle pain with Daniel Ryssman, M.D., an orthopedist and sports medicine physician from Mayo Clinic. We’ll review some of the common injuries to the ankle such as sprains and fractures as well as common chronic conditions of the foot such as plantar fasciitis and bunions. Dr. Ryssman delves into the best ways to prevent, diagnose, and treat these conditions as well as what, if any, imaging to order.
Specific topics discussed:
- Ankle sprains
- Ankle fractures
- Achilles’ tendon rupture
- Plantar fasciitis
- Bunions
- Metatarsalgia
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Friday Jun 11, 2021
Friday Jun 11, 2021
This episode is shared from Mayo Clinic Q&A and was recorded June, 2021
To claim credit visit: https://ce.mayo.edu/covid19podcast
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
If you've been vaccinated for COVID-19, you're able to go shopping, eat in restaurants and travel on airplanes without the same worry of becoming infected with COVID-19 that existed just months ago. But for those who are unvaccinated, getting infected with COVID-19 — even with just minor symptoms — should be a concern, according to Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group.
"For those who have been vaccinated, life is resuming back to a sense of normalcy," says Dr. Poland. "But for the unvaccinated, they now live in a dangerous phase of the pandemic, where we're seeing circulating variants that are much more transmissible and may cause worse cases of the disease than what happened last year at this time. I think the people who are unvaccinated may not realize that."
In this Mayo Clinic Q&A podcast, Dr. Poland also offers information on more COVID-19 studies underway and he talks about COVID-19 vaccine research protocols that will be able to help scientists with other vaccine research, such as HIV vaccine research. Also, he answers listener questions, such as, "Does someone who has already been infected with COVID-19, really need to be fully vaccinated for COVID-19 or would just a booster be needed?"
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jun 10, 2021
Regenerative Medicine Edition Ep.7: Preventing Osteoarthritis of the Knee
Thursday Jun 10, 2021
Thursday Jun 10, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Daniel Saris, M.D., Ph.D. (@sarisnl)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Osteoarthritis of the knee is extremely common, and it’s estimated that 1 in 2 people are likely to develop symptomatic knee osteoarthritis in their lifetime. Its known that damaged cartilage is the precursor to osteoarthritis. Many individuals have had partial or complete meniscectomies for meniscal tears in the past and those individuals were then likely to eventually develop knee osteoarthritis. What if damaged cartilage was repaired instead of surgically removed? Could that be an effective treatment recommendation we could give to our patients to help prevent or treat osteoarthritis? Our podcast guest today is Dr. Daniel Saris and he has some fascinating information related to cartilage damage and repair using regenerative medicine techniques.
Specific topics discussed:
- How meniscal damage relates to osteoarthritis
- Ability of cartilage to repair itself when damaged
- Repairing a damaged meniscus instead of a partial or complete meniscectomy
- Specific techniques of repairing cartilage
- Success in treating patients with cartilage repair
- Future treatment options for osteoarthritis using regenerative medicine
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jun 08, 2021
Tuesday Jun 08, 2021
Guest: Erin K. O'Brien, M.D. (@ErinOBrienMD)
Host: Amit K. Ghosh, M.D. (@AmitGhosh006)
Erin O’Brien, M.D., division chair of Rhinology in Rochester, MN, joins us again to provide an evidence-based update on anosmia and its prevalence in post-COVID patients. She reviews the postulated mechanism by which anosmia occurs in this group of patients, and how this effects patients’ safety, mental health, and overall wellbeing. Dr. O’Brien also gives an overview of treatment options, such as various methods of olfactory training, and what physicians need to know when counseling their patients with post-COVID anosmia.
Additional resources:
- Video on olfactory training: https://www.youtube.com/watch?v=Qrr0so6pFOs
- Abscent – resources for patients with anosmia: https://abscent.org/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday Jun 03, 2021
Regenerative Medicine Edition Ep.6: New Options for Treating Musculoskeletal Pain
Thursday Jun 03, 2021
Thursday Jun 03, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Shane A. Shapiro, M.D. (@ShaneShapiroMD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Musculoskeletal pain is extremely common and when severe, patients often gain significant benefit from joint replacements. However, until our patients reach the point where surgery is an option, our efforts to help patients with the chronic joint pain often leave much to be desired. A relatively new treatment approach has appeared in the past decade, musculoskeletal regenerative medicine. But does the research back up the numerous claims of benefit? This podcast will review the current treatment options available and future potential of regenerative medicine for musculoskeletal problems with Dr. Shane Shapiro, a sports medicine physician in the Department of Orthopedics at the Mayo Clinic. We’ll discuss the current regenerative products and therapies available to optimize patient outcomes, potential adverse effects of the therapies and the numerous claims by many clinicians regarding the benefit potential for regenerative medicine in musculoskeletal disease.
Specific topics discussed:
- Challenges of currently available traditional treatment for musculoskeletal conditions
- Benefits of stem cell injections for osteoarthritis
- Potential adverse effects of stem cell injections
- Currently available regenerative medicine therapies that have shown benefit to patients
- Validity of the many claims made by clinicians regarding the benefits of stem cell injections
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Tuesday Jun 01, 2021
Watching Out for Loperamide Abuse
Tuesday Jun 01, 2021
Tuesday Jun 01, 2021
Guest: Tyler S. Oesterle, M.D., M.P.H. (@OesterleMD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Opioid abuse remains a significant problem, and as law enforcement and regulatory agencies tighten access to prescription analgesics, individuals are seeking alternatives. It’s been discovered that when taken at very high doses, loperamide can produce similar effects to the opioid analgesics and the drug is inexpensive when compared to the price of both illicit and prescription opioids. As a result, loperamide abuse has become a significant problem. In this episode we discuss loperamide abuse with Tyler Oesterle, M.D., M.P.H., a psychiatrist at Mayo Clinic’s Rochester campus. We’ll review the typical central nervous system effects of high dose loperamide and the associated safety issues.
Specific topics:
- Current status of the opioid crisis in the U.S.
- Effects of loperamide in both therapeutic and excessive doses
- Reasons behind taking high dose loperamide in excessive doses
- Safety issues associated with high dose loperamide
- Potential of high dose loperamide leading to drug dependence
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Friday May 28, 2021
Friday May 28, 2021
This episode is shared from Mayo Clinic Q&A and was recorded May 24, 2021.
To claim credit visit: https://ce.mayo.edu/covid19podcast
Guest: Gregory A. Poland, M.D. (@drgregpoland)
Host: Halena M. Gazelka, M.D. (@hmgazelkamd)
The number of COVID-19 cases, hospitalizations and deaths in the U.S. continues to decline. However, cases of COVID-19 are increasing in younger populations.
"It's becoming a childhood disease," says Dr. Gregory Poland, an infectious diseases expert and head of Mayo Clinic's Vaccine Research Group. "Children have composed over 16,000 hospitalizations for COVID-19 and about 300 have died."
Meanwhile, each day brings fresh research news, including updates on possible side effects of the COVID-19 vaccines.
"We're collecting information as we go and have data on about 4.5 million people now," says Dr. Poland. "That's larger than we would have for any other vaccine."
In this Mayo Clinic Q&A podcast, Dr. Poland expands on these latest news items and puts the data in perspective. He also discusses vaccination rates, the possibility of mixing and matching vaccines for COVID-19 boosters, vaccination rates, and much more.
AskMayoExpert COVID-19 Resources: https://askmayoexpert.mayoclinic.org/navigator/COVID-19
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Thursday May 27, 2021
Thursday May 27, 2021
To claim credit for this episode, visit: www.ce.mayo.edu/regmedonline
Guest: Saranya Wyles, M.D. (@SWylesMDPhD)
Host: Darryl S. Chutka, M.D. (@ChutkaMD)
Much of regenerative medicine is relatively new and some of the future treatment capabilities have the potential to significantly change the way we practice medicine. How do you educate established clinicians as well as clinicians in training regarding this new practice? How do you educate the general public which has been misled by a variety of false claims regarding which medical conditions regenerative medicine can currently effectively treat? This podcast discusses how a relatively new medical field puts together an education program to inform others of its potential. Our guest is Saranya Wyles, M.D., a resident in the Department of Dermatology who has considerable experience in regenerative medicine education.
Specific topics discussed:
- Specific groups who need educating regarding the capabilities of regenerative medicine
- The importance in training the medical workforce regarding regenerative medicine
- What regenerative medicine means for the next generation of healthcare providers
- How to incorporate regenerative medicine concepts into an established medical school curriculum
- How to educate more advanced learn years such as residents and healthcare providers
- Obtaining an advanced degree in the field a regenerative medicine
Additional resources:
- International Society for Stem Cell Research (ISSCR): https://www.isscr.org/
- The ISSCR Patient Handbook on Stem Cell Therapies: https://www.closerlookatstemcells.org/patient-resources/
- Regenerative medicine curriculum for next-generation physicians: https://www.nature.com/articles/s41536-019-0065-8
- Digital regenerative medicine and surgery pedagogy for virtual learning in the time of COVID-19: https://www.futuremedicine.com/doi/full/10.2217/rme-2020-0106
Additional educational opportunities from Mayo Clinic:
- https://www.mayo.edu/research/centers-programs/center-regenerative-medicine/education
- https://college.mayo.edu/academics/biomedical-research-training/phd-program/tracks/regenerative-sciences/
Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.