Mayo Clinic Talks

Alternative Therapies for Hyperlipidemia: The Lipid-ome of Lowering Cholesterol

Host: Darryl S. Chutka, M.D. [@ChutkaMD]

Guest: Stephen Kopecky, M.D. [@DrSteveKopecky]

Hyperlipidemia is extremely common in the U.S., and we have a variety of pharmacologic agents which are very effective in treating this condition and improving our patients’ lipid profile. Yet there are patients who have elevated lipids but may not meet the criteria for pharmacologic therapy and other patients who don’t tolerate the medications we commonly prescribe. What are the alternative treatments available for managing hyperlipidemia and how effective are they?  How do they compare with pharmacologic therapy? We’ll discuss these issues and more in this podcast with our guest, preventive cardiologist Stephen Kopecky, M.D., from the Mayo Clinic. 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Hand & Wrist Disorders: Lend Me a Hand (& Wrist)

Host: Darryl S. Chutka, M.D. [@chutkaMD]

Guest: Sanjeev (Sanj) Kakar, M.D. [@sanjkakar]

The hand and wrist are very complex parts of our anatomy and composed of multiple tendons, muscles, and nerves. The hand also contains over 30 bones. Hand or wrist complaints are some of the more common reasons patients come to their primary care provider, and at times, the cause can be quite elusive. We need to be able to accurately assess the patient’s symptoms, diagnose the various disorders and determine which ones need to be referred for specialty care and which ones we can manage on our own. In this podcast, we’ll discuss some of the most common hand and wrist disorders with Sanjeev Kakar, M.D., a hand specialist from the Department of Orthopedics at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Chronic Kidney Disease: What Primary Care Providers Need to Know

Host: Darryl S. Chutka, M.D. [@chutkaMD]

Guest: Mira T. Keddis, M.D. [@keddis_mira]

Chronic kidney disease can have a major impact on a patient’s quality of life; reducing their energy level, impacting their diet and may limit medications or alter medication dosages we prescribe. It’s estimated that kidney disease affects nearly 40 million people in the U.S. or 15% of the population, and two out of five adults with severe kidney disease don’t even know they have it. As primary care providers, we need to know how to prevent kidney disease, how we assess renal function and how to manage those with moderate to severe renal impairment. Our guest for today’s podcast is Mira T. Keddis, M.D., a nephrologist at the Mayo Clinic in Scottsdale, Arizona.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Glaucoma: Not So Easy on the Eyes

Guest: Cheryl L. Khanna, M.D.

Host: Darryl S. Chutka, M.D.  [@chutkaMD]

Glaucoma is a very common eye disease affecting more than 70 million people worldwide and it’s a leading cause of blindness, accounting for over 12% of blindness around the world. While it tends to be more common in older individuals, it can occur in younger patients as well. There are a variety of types of glaucoma as well as several new treatment options available. In this podcast, we’ll discuss the various types of glaucoma, its treatment options and what we should do as primary care providers to help patients get a proper diagnosis and prevent the vision loss which can be associated with glaucoma. Our guest is Cheryl L. Khanna, M.D., an ophthalmologic surgeon at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Abortion: What the Primary Care Provider Should Know

Guest: Regan N. Theiler, M.D., Ph.D.

Host: Darryl S. Chutka, M.D. @chutkaMD

Abortion is a common procedure. three out of ten pregnancies and six out of ten unintended pregnancies end with an induced abortion. Overall, about one in four women in the U.S. will have an abortion by the age of 45 years. The U.S. Supreme Court’s June 2022 ruling to overturn Roe vs. Wade has shifted the legal battle over abortion to the states, resulting in some states prohibiting abortion and others moving to safeguard it. The topic for this podcast is abortion and what the primary care provider should know. Our guest is Regan N. Theiler, M.D., Ph.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Faculty Twitter: 

[@chutkaMD; https://twitter.com/ChutkaMD] 

Vaccine Recommendations: 2022 Important Updates

Host: Darryl S. Chutka, M.D. [@chutkaMD]

Guest: Robert M. Jacobson, M.D. [@RobertJMD]

Immunizations are one of the greatest success stories in modern medicine and it’s estimated that they’ve saved more lives and prevented more disabilities than any other medical intervention. They’re probably responsible, more than any other medical advance, in contributing to our increased longevity as a population. They’re also extremely cost-effective and their benefits far outweigh the very small risks they carry. This podcast will review new information regarding immunizations and how we as clinicians can increase our patients’ immunization rates. Our guest is Robert M. Jacobson, M.D., a pediatrician, and expert in immunizations from the Department of Pediatrics at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Faculty Twitter: 

[@chutkaMD; https://twitter.com/ChutkaMD] 

[@RobertJMD; https://twitter.com/robertjmd]

What To Know About Home Genetic Testing

Guest: Matthew J. Ferber, Ph.D.

Host: Darryl S. Chutka, M.D. [@chutkaMD]

Over the past decade or so, we’ve learned a great deal about the human genome, and this has allowed us to determine which medical conditions our patients are at an increased risk of developing and which medications may be best suited for their medical problems. In addition to the clinical genetic tests we use in our practice, direct to consumer home genetic testing has become extremely popular. This podcast will review home genetic testing and what information patients can expect with these tests, whether the information they receive is accurate and how home genetic testing differs from the genetic tests we order. Our guest is Matthew J. Ferber, Ph.D., a clinical molecular geneticist at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Evaluation & Management of Osteoporosis: Make No Bones About It

Host: Darryl S. Chutka, M.D. (@chutkaMD) https://twitter.com/ChutkaMD

Guest: Kurt A. Kennel, M.D.

Hip fractures have had a major impact on our healthcare system with an economic burden estimated to be over $20 billion per year. Due to the increasing age of our population, they’ll have an even greater impact in the future. In addition to the economic burden, hip fractures often result in major changes to one’s lifestyle. As a result, the detection, prevention and management of osteoporosis becomes an important health strategy. The topic for this podcast is osteoporosis and our guest is Kurt A. Kennel, MD., a Mayo Clinic Endocrinologist, and specialist in bone metabolism.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Reducing Medical Supply Chain Vulnerability: Now You See It, Now You Don’t

Guest: Pritish K. Tosh, M.D. (@DrPritishTosh)

Host: Darryl S. Chutka, M.D. (@chutkaMD)

The COVID-19 pandemic exposed the vulnerability of the medical product supply chain and its impact on providing optimal healthcare. The spread of the disease was accompanied by not only shortages of personal protective equipment but also medications and many other products we depend on every day in our clinical practice. We’ve learned that we cannot provide adequate or timely health care when there are shortages of important products. As a result, the health of our patients and healthcare providers has been endangered. It’s also resulted in a rationing of care and an increased risk of error as we’re forced to use sub-standard or replacement products. It’s caused us to look for new solutions to reduce our medical supply chain vulnerabilities. Our guest for this podcast is Pritish K. Tosh, M.D., an infectious disease specialist at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Twitter Handles:

(@chutkaMD); https://twitter.com/ChutkaMD 

(@DrPritishTosh); https://twitter.com/drpritishtosh

Colon Polyps: A Real Bum-mer

Guest: John B. Kisiel, M.D. (@DrJohnKisiel)

Host: Darryl S. Chutka, M.D. (@chutkaMD)

Colon polyps are relatively common in our population and, in most cases, are relatively easily found and removed, thereby reducing one's risk of developing colorectal cancer. What are the various types of colon polyps and which polyps have a greater tendency to become malignant? How long does it take a polyp to develop into colon cancer and how often does colonoscopy miss polyps?  These are just some of the topics we’ll discuss in today’s podcast. Our guest is John B. Kisiel, M.D., a gastroenterologist at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Genes & Your Health Edition: Precision Medicine for Obesity: From Phenotypes to Multi Omics

Host: Denise M. Dupras, M.D., Ph.D.

Guest: Andres J. Acosta, M.D., Ph.D. (@dr_aac)

The obesity epidemic continues to escalate in the United States and obesity rates are increasing around the world. It is estimated that by 2030, 50% of adults and 25% of children worldwide will be obese. Patients are the interaction of their genetics and environment; this episode explores the importance of understanding the mechanisms behind food intake regulation and weight to develop individualized therapies to treat obesity. Our guest for this episode is Andres J. Acosta, M.D., Ph.D., a physician-scientist at Mayo Clinic in Rochester, Minnesota. He is also an assistant professor of medicine at Mayo Clinic College of Medicine and Science, and principal investigator of the Precision Medicine for Obesity Laboratory.

Uterine Fibroids: Under Pressure

Guest: Elizabeth (Ebbie) A. Stewart, M.D.

Host: Darryl S. Chutka, M.D.

Uterine fibroids are the most common tumor of the female reproductive tract and women who are approaching menopause are at greatest risk for having them. In most cases, they don’t produce symptoms and only a minority of women require treatment. The topic for this podcast is uterine fibroids and we’ll discuss how fibroids can be diagnosed, their most common symptoms, who requires treatment and some of the latest treatment options with our guest, Elizabeth A. Stewart, M.D., from the Department of Obstetrics and Gynecology at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Genes & Your Health Edition: Epigenomics Research – Understanding Genetics of Treatment Resistance

Guest:   Alexandre Gaspar Maia, Ph.D. (@gasparma1a)

Host: Denise M. Dupras, M.D., Ph.D.

Epigenomics is a fascinating field in which researchers chart the locations and understand the functions of all chemical tags that mark the genome. The epigenome is the first boundary from the exterior world to our DNA sequence, and it can change dramatically. This episode discusses the state of the art of epigenomics analysis and the epigenome in the context of specific cells. Additionally, it explores the future of epigenomics for individualized medicine and in better understanding genetics of treatment resistance. The guest for this episode is Alexandre Gaspar Maia, Ph.D., an assistant professor in the Functional Genomics Laboratory at Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Scoliosis: Around The Bend

Host: Edward R. Laskowski, M.D

Guest: Anthony A. Stans, M.D.

The evaluation and treatment of scoliosis is an area that has created some controversy over the years.  Should we be screening kids in school?  When do we brace kids with scoliosis?  And what are the indications for surgery? To help us answer these questions and more, I am delighted to welcome Anthony A. Stans, M.D., a consultant in the Division of Pediatric Orthopedic Surgery with special interest in the treatment of spinal deformity.  He is past Chair of the Mayo Clinic Division of Pediatric Orthopedic Surgery and past Surgeon in Chief for the Mayo Clinic Children’s Center.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Genes & Your Health Edition: Neurodegenerative Brain Disease

Guest: Bradley F. Boeve, M.D.

Host: Denise M. Dupras, M.D., Ph.D.

Family history is so important in deciphering genetic causes for neurodegenerative disorders. As we study polygenetic situations, we are learning that often it is not just one gene, but the contribution of multiple genes that lead to the presentation of a patient with cognitive or brain function deterioration that occurs at a variable rate. In this episode, we discuss genes and neurodegenerative brain disease, and our guest is Bradley F. Boeve, M.D., a consultant in the Department of Neurology and the Center for Sleep Medicine, as well as a professor of neurology at the Mayo Clinic in Rochester, Minnesota.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Psoriasis: Let’s Talk Rash-tionally

Host: Darryl S. Chutka, M.D. @chutkaMD

Guest: Jason C. Sluzevich, M.D.

Psoriasis is a somewhat atypical dermatologic condition which can come and go over time. In many, there may be seasonal effects and in some, psoriasis can have an associated arthritis. It has a characteristic distribution and while it has no cure, there are a variety of established and new treatment options. In this podcast, we’ll review how to diagnose psoriasis, its characteristic appearance, its associated arthritis, and management strategies with Jason C. Sluzevich, M.D., a dermatologist from the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Genes & Your Health Edition: Breast Cancer & SNPs- What Are They & What Do We Know?

Guests: Sandhya Pruthi, M.D. (@DrSandhyaPruthi)

Host: Denise M. Dupras, M.D., Ph.D.

What is precision prevention? As providers, what can we do to best determine who is at high risk for breast cancer, and when to make appropriate decisions about interventions to reduce an individual’s risk for getting breast cancer? In this episode of our Genes & Your Health edition from the Center for Individualized Medicine, we will learn more about breast cancer, breast cancer genes and the role of single nucleotide polymorphisms (SNPs) in breast cancer risk assessment. Our guest is Sandhya Pruthi, M.D., a Mayo Clinic physician in breast disease and a consultant and Professor of Medicine in the Department of General Internal Medicine in Rochester, Minnesota.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Helping Your Patients Live Younger Longer

Host: Darryl S. Chutka, M.D.  @ChutkaMD

Guest: Stephen Kopecky, M.D.

Most of us want to live longer, but we want to live a healthy life and avoid the many health problems associated with growing older. Many of the health issues associated with aging have significant morbidity and have the potential to significantly affect our quality of life. Do we know how to avoid these health problems and stay healthy into our older ages? What should we be advising our patients to help them live younger longer? We’ll discuss these questions with our guest today, Stephen Kopecky, M.D., a preventive cardiologist at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Genes & Your Health Edition: Polycystic Kidney Disease & Genetic Testing - Aiming for Accurate Diagnosis

Guest: Fouad T. Chebib, M.D.

Host: Denise M. Dupras, M.D., Ph.D.

What is polycystic kidney disease? Is it all genetic? As providers, what should we be considering and what patients should we think about screening with genetic testing? Join this episode of our Genes & Your Health edition from the Center for Individualized Medicine to learn more about the role of genes in polycystic kidney disease. This episode features Fouad T. Chebib, M.D., a Mayo Clinic nephrologist from Jacksonville, Florida, whose specialty is in polycystic kidney disease.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Genes & Your Health Edition: Exposomics - The Next Frontier

Guest: Konstantinos N. Lazaridis, M.D.

Host: Denise M. Dupras, M.D., Ph.D.

What does the exposome mean? In this episode, we will define the exposome and explore how assessing exposures in an organized fashion will help us better understand the gene environment interaction. The guest for this episode of our Genes & Your Health edition from the Center for Individualized Medicine is Konstantinos N. Lazaridis, M.D., a Mayo Clinic physician in the Division of Gastroenterology and Hematology, as well as the Bernard and Edith Waterman Director, Microbiome Program, Center for Individualized Medicine and Carlson and Nelson Endowed Director, Center for Individualized Medicine.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Monoclonal Gammopathy of Undetermined Significance (MGUS)

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Guest: Wilson I. Gonsalves, M.D.

Monoclonal gammopathies represent abnormal proteins produced by plasma cells. The most common monoclonal gammopathy is monoclonal gammopathy of undetermined significance or MGUS. While MGUS itself is not a malignancy and doesn’t require treatment, patients with MGUS have an increased risk of developing a variety of hematologic malignancies and therefore do require surveillance. The topic for today’s podcast is monoclonal gammopathy of undetermined significance and our guest is Wilson I. Gonsalves, M.D., a hematologist and oncologist from the Division of Hematology at the Mayo Clinic. We’ll discuss how to diagnose MGUS, who is more likely to develop this condition and how patients with it should be followed. 

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Mayo Clinic Q&A: Updated COVID-19 boosters target omicron variants

This episode is shared from Mayo Clinic Q&A and was recorded on August 31, 2022

Guest: Gregory A. Poland, M.D. (@drgregpoland)

Host: Halena M. Gazelka, M.D. (@hmgazelkamd)

The first significant change to COVID-19 vaccines since their rollout came this week as the Food and Drug Administration granted emergency use authorization for updated Moderna and Pfizer COVID-19 boosters aimed at the omicron variants. The Centers for Disease Control and Prevention (CDC) also signed off on the recommendation, clearing the way for the new COVID-19 booster to be administered.

The new boosters are bivalent vaccines, meaning they target more than one strain of the virus. The new formulation targets the BA.4 and BA.5 omicron variants, in addition to the original coronavirus strain. BA.5 is responsible for nearly 90% of all new COVID-19 cases in the U.S., according to the CDC.

The Pfizer bivalent booster is approved for people 12 and up if they have already received their primary COVID-19 vaccine series and it has been at least two months since their last vaccine dose. The Moderna bivalent booster is available on the same timeline to people 18 and up.

"This booster recommendation is in anticipation that there will be yet another surge as college students, grade school and high school students are gathering back together," explains Dr. Gregory Poland, head of Mayo Clinic's Vaccine Research Group. "We're also preparing for cooler weather, meaning more indoor activities, family gatherings and the holidays — often without masks, unfortunately. We still need to take COVID seriously."

Another big concern for vaccine experts is the upcoming flu season. The Southern Hemisphere is often an indicator of what's to come for the U.S. Australia's flu season exceeded its five-year average, particularly affecting children under age 5, according to a recent report.

Experts worry that the relaxing of masking and social distancing recommendations that were in place for COVID-19 purposes the past two winters will be a factor. These measures also protected people from the flu.

"When cold weather moves us indoors, a high viral circulation occurs in schools and other indoor settings. I think we are very likely to see a bad flu year," says Dr. Poland. "Now I know we've been predicting that for two years, but for the most part, people wore masks and it didn't happen. I don't think that'll be the case this year. People are not wearing masks, and we are very likely to get hit hard by influenza."

On the Mayo Clinic Q&A podcast, Dr. Poland discusses the latest COVID-19 news and touches on other news, including monkeypox, polio and the upcoming flu season.

 

Plantar Fasciitis: Best Step Forward

Host: Joshua D. Luciew, P.A.-C.

Guest: Arthur J. De Luigi, D.O., M.H.A. (@DrDeLuigi, https://twitter.com/drdeluigi)

Heel and foot pain can be a burdensome symptom for our patients, as discomfort can be experienced with each step they take, hindering locomotion.

Many different patient populations are required to be on their feet for their job or for various wellness goals, which can exacerbate their painful heel and foot or deter them from exercise.

In this episode, we will explore the most common cause of heel and foot pain: plantar fasciitis. Listeners will learn from a Mayo Clinic specialist in Physical Medicine and Rehabilitation how plantar fasciitis develops, how it is properly diagnosed, and learn the best approaches for treatments of this condition to help patients resume their previous physical activities, pain-free.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Peripheral Neuropathies: On Pins and Needles

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Guest: Julie A. Khoury, M.D.

Peripheral neuropathy is a relatively common neurologic condition we frequently see in primary care. Some patients may describe the symptoms as paresthesias and they represent a minor nuisance, however others may have very painful dysesthesias. Since some peripheral neuropathies are reversible, we need to know when to suspect a peripheral neuropathy, how to evaluate patients who have them and the possible treatment options. We’ll discuss peripheral neuropathies in this podcast with Julie A. Khoury, M.D., a neurologist at the Mayo Clinic in Phoenix, Arizona.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.

Kidney Stones: This Too Shall Pass

Host: Darryl S. Chutka, M.D. (@ChutkaMD)

Guest: Ivan E. Porter, II M.D.

Kidney stones are quite common and represent one of the most common disorders of the urinary system. When symptomatic, stones are relatively easy to diagnose as they tend to cause a very characteristic clinical presentation. While most stones will pass through the urinary system, others will require a variety of treatment options. The topic for today’s podcast is kidney stones and we’ll discuss the diagnosis, management, and prevention of stones with Ivan E. Porter, II M.D., a nephrologist at the Mayo Clinic.

Connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.